I-Acetyl hexapeptide -8, eyaziwa ngokuba yi-akirelin kunye ne-hexapeptide.I-Acetyl hexapeptide -8 ikwabizwa ngokuba yi "botulinum toxin-like"/"smear botulinum toxin" ngabantu abaninzi.Kunokuthiwa i-aquiline yi-polypeptide echasene nemibimbi enesiphumo esingcono kune-toxin ye-botulinum.
Njengoko sonke siyazi, i-toxin ye-botulinum yimveliso yobuhle efuna inaliti.Kuyingozi kakhulu ukuyisebenzisa, kwaye kufuneka isetyenziswe ziingcali.Idosi kufuneka ilawulwe ngokungqongqo, kodwa isenako ukuphepha iziphumo ebezingalindelekanga ezahlukeneyo ezinjengokuqina kobuso kunye nokukhubazeka kobuso.
I-Argireline yaqinisekiswa kwiimvavanyo zomntu zabenzi bezothambiso: ubunzulu bombimbi obuphakathi kwehle nge-16.9% kunye ne-27.0% emva kwe-15 kunye neentsuku ze-30 kunye ne-10% isisombululo se-Argireline, kunye nomthamo wokushwabana kwehle ngo-20.6% kunye nobude bombimbi behla nge-15.9% emva kuphela 7 iintsuku kunye 2% Argireline isisombululo.Kuyabonakala ukuba umphumo we-achillerin kwimibimbi ubaluleke kakhulu.
Imibimbi eluswini lobuso bomntu ikakhulu ibangelwa kukuphumla kwe-collagen kunye nokucutheka okungafunekiyo kwemisipha.Ukuba ukucutheka kwezi zihlunu kunokulawulwa, izihlunu zesikhumba zinokukhululeka ukukhulula imibimbi kwaye zifezekise injongo esisiseko yokususa imibimbi.
I-toxin ye-botulinum, njengendlela esebenzayo yokususa imibimbi, iyaziwa ngokubanzi ngesiphumo sayo esihle kakhulu.Nokuba iya kubangela imingcipheko enkulu emva kokusetyenziswa, kuya kuhlala kukho inani elikhulu labathengi abazimisele ukuyisebenzisa.I-Polypeptide yahlukile.Njengemveliso ye-organic synthetic, xa isetyenziswe njengesithako sokuthambisa, inokutshatyalaliswa ngokukhawuleza ibe yi-amino acids yamahhala ekugxininiseni okuphantsi.Ulandelelwano lwayo oluphambili lusekelwe kumzimba womntu kunye nendlela yokusebenza kwayo yendalo.Iimpawu zeepeptide ezincinci zemolekyuli zibenza babe nokugqithiswa kakuhle kwe-transdermal kwaye bafakwe kakuhle ngumzimba womntu.I-Acetyl hexapeptide -8 ikhusela i-nerve ekudluliseni ulwazi lwe-muscle contraction ngokusebenzisa indlela efana ne-toxin ye-botulinum, ukwenzela ukuba i-muscle ayinakho isivumelwano sokuphelisa imibimbi.Inomsebenzi ophezulu wokuchasa imibimbi kunye neziphumo ebezingalindelekanga ezimbalwa, kwaye isetyenziswe ngokubanzi kwizithambiso ezahlukeneyo zokugqibela.
Singumenzi wepolypeptide eTshayina, esineminyaka eliqela yamava aqolileyo kwimveliso yepolypeptide.I-Hangzhou Taijia Biotech Co., Ltd. yingcali yomenzi we-polypeptide ekrwada, enokubonelela amashumi amawaka ezinto ezikrwada ze-polypeptide kwaye inokwenziwa ngokweemfuno.Umgangatho weemveliso ze-polypeptide ugqwesileyo, kwaye ukucoceka kunokufikelela kwi-98%, eye yaqatshelwa ngabasebenzisi emhlabeni wonke.